Long-term survival in small cell carcinoma of the lung |
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| Affiliation: | 1. Department of Oral and Maxillofacial Surgery, Truman Medical Center, 2301 Holmes, Kansas City, MO 64108, USA;2. Department of Diversity and Inclusion, Truman Medical Center, 2301 Holmes, Kansas City, MO 64108, USA;3. Department of Diversity and Inclusion, UMKC School of Dentistry, 650 E. 25th Street, Kansas City, MO 64108, USA;1. National Center for Space Exploration Research, Cleveland, OH, United States;2. NASA John H. Glenn Research Center, Cleveland, OH, United States;1. Department of Radiology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom;2. Department of Nuclear Medicine, The Christie National Health Service Foundation Trust, Manchester, United Kingdom;3. Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom;4. Department of Clinical Oncology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom;5. Division of Pharmacy, University of Manchester, Manchester, United Kingdom;6. Department of Clinical Oncology, Addenbrooke’s Hospital, Cambridge, United Kingdom;7. Department of Clinical Oncology, The Royal Marsden National Health Service Foundation Trust, Surrey, United Kingdom;8. Department of Clinical Oncology, Northern Ireland Cancer Centre, Belfast City Hospital, Belfast, United Kingdom;9. Department of Clinical Oncology, Northern Centre for Cancer Care, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom;10. Department of Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom;11. Department of Clinical Oncology, Leeds Cancer Centre, St James’s Hospital, Leeds, United Kingdom;12. Department of Nuclear Medicine, Manchester University National Health Service Foundation Trust, Manchester, United Kingdom;1. Legal Medicine Consultants, 1150 N Loop 1604 West, Suite 108-625, San Antonio, TX 78248, USA;2. Department of Clinical Medicine K1, University of Bergen, Bergen, Norway;3. Department of Neurosurgery, Haukeland University Hospital, Bergen 5021, Norway;4. Deans and Lyons, LLP, 1001 Fannin, Houston, TX 77002, USA |
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| Abstract: | We analyzed the long-term survivors in a group of 255 patients with newly diagnosed small cell carcinoma of the lung (SCCL) between January 1978 and July 1983. Long-term survivors were defined as those patients free of cancer 2 years after initiation of therapy. Only 6 patients (2.5%) were free of disease at this time. Two patients relapsed at 29 and 40 months from the start of chemotherapy. Both patients were retreated with chemotherapy, and one of them achieved a complete response. Despite the increase in median survival in SCCL with chemotherapy over the past 10 years, long-term prognosis remains very poor employing standard treatments. |
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