肺癌患者化疗前后血清SIL-2R,CEA含量检测的临床意义

目的 :本文探讨了肺癌患者化疗前后血清SIL - 2R和CEA水平的变化。方法 :应用放免法测定 31例肺癌患者化疗前后血清SIL - 2R和CEA含量 ,并与 35名正常健康人作比较。结果 :肺癌患者化疗前血清SIL - 2R和CEA水平非常显著地高于正常人 (P <0 0 1) ,化疗后 3个月血清CEA水平与正常人比较无显著性差异 (P >0 0 5 ) ,而SIL - 2R仍高于正常人 (P <0 0 5 )。结论 :测定血清SIL - 2R和CEA水平可作为判断疗效的参考。

Clinical Sigificance of Changes of Serum Levels of SIL-2R and CEA in Patients with Lung Carcer After Chemotherapy

Objective To investigate the changes of serum levels of SIL-2R and CEA after chemotherapy in patients with lung cancer. Methods Serum levels of SIL-2R (with ELISA) and CEA (with RIA) were measured in 31 patients with lung cancer both before and after chemotherapy as well as in 35 cantrols. Results Before chemotherapy, both serum SIL-2R and CEA levels in the patients were significantly higher than those in the controls (P<0.01). Three months after chemotherapy, the serum CEA levels in the patients were about the same as those in controls (P>0.05), but the serum SIL-2R levels in the patients remained significantly higher than those in the controls (P<0.05). Conclusion Determination of changes of serum SIL-2R and CEA levels after chemotherapy might be helpful for predicting the treatment outcomes in patients with lung cancer.