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IL-1基因多态性与胃癌易感性关系的研究进展
引用本文:郑磊贞,蔡威. IL-1基因多态性与胃癌易感性关系的研究进展[J]. 上海交通大学学报(医学版), 2007, 27(2): 230-233
作者姓名:郑磊贞  蔡威
作者单位:上海交通大学,医学院新华医院肿瘤科,上海,200092;上海交通大学,医学院新华医院肿瘤科,上海,200092
基金项目:上海交通大学医学院基金
摘    要:胃癌是危害人类生命健康的主要恶性肿瘤之一,其病因复杂,是遗传因素和环境因素综合作用的结果。近年来的研究表明,细胞因子白细胞介素1(IL-1)的基因多态性,可能在胃癌的发生、发展中起一定作用。本文就该方面的研究进展进行综述。

关 键 词:白细胞介素1  胃癌  易感性  基因多态性
文章编号:0258-5898(2007)02-0230-04
修稿时间:2006-06-18

Research progress of relationship between IL-1 gene polymorphisms and gastric cancer susceptibility
ZHENG Lei-zhen,CAI Wei. Research progress of relationship between IL-1 gene polymorphisms and gastric cancer susceptibility[J]. Journal of Shanghai Jiaotong University:Medical Science, 2007, 27(2): 230-233
Authors:ZHENG Lei-zhen  CAI Wei
Affiliation:Department of Oncology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China
Abstract:Gastric cancer is one of the most common cancers in the world.The causes and pathogenesis of gastric cancer are complex,and both genetic and environmental factors may contribute to the development of gastric cancer.Recent studies have revealed that polymorphisms of interleukin-1(IL-1) gene may be associated with the risk of gastric cancer and the progress of this issue is thus reviewed.
Keywords:interleukin-1  gastric cancer  susceptibility  polymorphism
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