丁苯酞注射液防治TIA患者进展为脑梗死的临床观察

目的观察临床上采用丁苯酞注射液防治TIA患者进展为脑梗死的作用效果。方法120例TIA患者平均分为两组:基础治疗方案为控制血压、血糖、血脂和静脉滴注丹参川芎嗪,对照组、观察组分别加用拜阿司匹林和丁苯酞注射液,疗程均为2周,随访4周记录两组发生脑梗死的病例数,并以ABCD2评分量表对两组TIA患者进行预后评估;观察并比较两组TIA患者治疗的临床效果。结果观察组进展为脑梗死发生率明显较低,与对照组相比P<0.05;观察组ABCD2评分低于对照组(P<0.01);根据ABCD2评分评估预后,观察组中、高危病例占比低于对照组(P<0.05);观察组临床有效率高于对照组(P<0.01)。结论丁苯酞注射液防治TIA患者进展为脑梗死的临床效果显著。

Clinical Observation of Butylphthalide Injection in Preventing and Curing TIA Patients From Progressing to Cerebral Infarction

Objective To observe the effect of butylphthalide injection on the prevention and treatment of cerebral infarction in TIA patients.Methods 120 TIA patients were divided into two groups on average:the basic treatment was to control blood pressure,blood sugar,blood lipid and intravenous drip of Salvia miltiorrhiza and ligustrazine.The control group and the observation group were treated with aspirin and butylphthalide injection respectively for two weeks.The patients of cerebral infarction in the two groups were followed up for 4 weeks and recorded with ABCD2 scale.The prognosis of TIA patients in the two groups was evaluated,and the clinical effects of TIA patients in the two groups were observed and compared.Results The incidence of cerebral infarction in the observation group was significantly lower than that in the control group(P<0.05);the ABCD2 score in the observation group was lower than that in the control group(P<0.01);according to the ABCD2 score,the proportion of highrisk cases in the observation group was lower than that in the control group(P<0.05);and the clinical effective rate in the observation group was higher than that in the control group(P<0.01).Conclusion Butylphthalide injection has a significant clinical effect in preventing and treating TIA patients from progressing to cerebral infarction.