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The utility of a 5th nap in multiple sleep latency test
Authors:Rexford Muza  Dimosthenis Lykouras  Kate Rees
Affiliation:1.Sleep Disorders Centre, Nuffield House, Guy’s and St Thomas’ NHS Trust, London, UK; 2.Department of Pulmonary Medicine, University Hospital of Patras, Rio Patras, Greece; 3.School of Medical Education, King’s College London, London, UK
Abstract:

Background

This is the first study that aimed to look specifically at the utility of the 5th nap in the multiple sleep latency test (MSLT), a test used to assist in the diagnosis of narcolepsy.

Methods

Data was retrospectively collected from the Sleep Disorders Centre of a Tertiary Hospital on patients that had a 5th nap during their MSLT from the 08th November 2011 to 12th November 2014.

Results

Fifty-three patients had a 5th nap performed out of 378 MSLT studies. In 16% of cases a diagnosis of narcolepsy was given directly due to the inclusion of the 5th nap on the MSLT. Here a 5th nap allowed diagnostic criteria of mean sleep latency <8 minutes and >2 SOREMPS to be met. In 53% of cases the mean sleep latency increased due to 5th nap inclusion; the mean sleep latency of the first four naps was 5.6 vs. 6.7 after inclusion of the 5th nap.

Conclusions

The 5th nap is not often performed within the MSLT studies. Our study shows that only a few patients may benefit from a 5th nap opportunity which also led to increase of the mean sleep latency at the expense of extra time, cost, labour and increased patient anxiety.
Keywords:Narcolepsy   multiple sleep latency test (MSLT)   sleep onset rapid eye movement (SOREM)   sleep diagnostics
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