云南石仙桃中酚类成分的研究

 目的　分离鉴定云南石仙桃中的酚类成分。方法　 95 %乙醇提取 ,硅胶柱色谱分离 ,用UV,IR,MS,¹H NMR ,¹³ C-NMR和HMBC等方法确定结构。结果　分得 4个酚类成分 ,分别为eulophiol(Ⅰ) ,lusianthridin(Ⅱ) ,densiflorolB(Ⅲ )和batatasin Ⅲ (Ⅳ) ,以及 4个其他类型的化合物 3,5-二甲氧基-4-羟基苯丙酮 (3,5 dimethoxy-4-hydroxypropiophenone ,V);(24R)-6β-hydroxy-24-ethyl cholest-4-en-3-one(VI) ;5α,8α-epidioxy-24?-methylcholesta-6,22-dion-3β-ol(Ⅶ)和胡萝卜苷 (daucosterol,Ⅷ )。 结论　以上化合物均为首次从石仙桃属植物中分离得到。化合物Ⅰ和Ⅱ的碳谱数据为首次报道

Study on phenolic constituents of Pholidota yunnanensis

OBJECTIVE To isolate and identify the phenolic constituents from Pholidota yunnanensis Rolfe METHODS The chromatography on silica gel was used for the isolation and purification of the constituents The structures were determined by UV,IR,MS,¹H-NMR,¹³C-NMR and HMBC spectral analyses RESULTS Four phenolic constituents and four other compounds were obtained and identified as following: eulophiol(Ⅰ);lusianthridin(Ⅱ);densiflorol B(Ⅲ);batatasin Ⅲ(Ⅳ);3,5-dimethoxy-4-hydroxypropiophenone(Ⅴ);(24R)-6β-hydroxy-24-ethyl-cholest-4-en-3-one(Ⅵ), 5α, 8α-epidioxy-24?-methylcholesta-6;22-dion-3β-ol(Ⅶ) and daucosterol(Ⅷ). CONCLUSION All above compounds were isolated from Genus Pholidota for the first time The ¹³C-NMR data of compound Ⅰand Ⅱ were reported for the first time.