A Case of Hepatocellular Carcinoma Developed on Polycystic Disease of the Liver with Cirrhosis

A case of hepatocellular carcinoma associated with polycysticdisease of the liver and posthepatitic cirrhosis in a 56-year-oldKorean woman was described. She was first admitted because ofepigastralgia, irradiated back pain and general fatigue. Onthe liver scan a relative cold area was demonstrated. The celiacangiography revealed multiple avascular areas indicating cysticlesions. The exploratory laparotomy confirmed the presence ofpolycystic disease of the liver with cirrhosis. Four years afterthe first admission, she underwent an appendectomy. At the timeof operation, the surgeon suspected the presence of hepatocellularcarcinoma, and she was admitted for the second time to our hospital.The minimal elevation of serum -fetoprotein was observed. Thedevelopment of hepatocellular carcinoma was confirmed by theceliac angio graphy, and a partial lobectomy of the liver wasperformed. Four months after the operation she died of hepaticfailure. Of the four reported cases of hepatocellular carcinoma associatedwith polycystic disease of the liver including this case, allhad liver cirrhosis, and serum HBs-Ag was positive in all ofthe three cases examined.