性早熟14例临床分析

本文对我院治疗的14例性早熟患儿的病因进行分析。通过病史、体征、辅助检查及内分泌测定,发现真性性早熟8例,假性性早熟6例。6例假性性早熟采用去除病因及对症治疗;8例真性性早熟采用安宫黄体酮片治疗,每日3次,每次4～8㎎口服,并根据病情及雌激素水平调整剂量:经3～6个月治疗,6例月经停止,乳腺萎缩,激素水平下降。本文认为采取有效措施预防性早熟的发生十分重要。

Sexual prccocity.Clinical analysis of 14 cascs.

Fourteen cases of sexual prccocity in our hospital were analyzed for the causcs. By casehistory, physical signs, auxiliary examination and endocrine determination, 8 were fourd to be true precocity, the rest were precocious pseudopuberty. The 6 cases of precocious pseudopuberty were treated by eliminating the pathogenic factors and, ifnecessary, treating the specific manifestions. For the 8 true precocity oral medroxyprogesterone was given, 4 to 8mg each time, 3 times a day. The dose was adjusted according to the severity and estrogen level. After 3 to 6 month's treatment, 6 cases of the true precocity had their menstruation and breast budding stoppend and the steroid levels lowered. The paper suggested that preventive measures were important in management of sexual precocity.