Treatment of sydenham chorea with intravenous immunoglobulin |
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| Authors: | Walker Kathleen Brink Anita Lawrenson John Mathiassen Wendy Wilmshurst Jo M |
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| Affiliation: | Rheumatic Fever Clinic, Department of Cardiology, Red Cross Children's Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa. buley@iafrica.com |
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| Abstract: | Sydenham chorea is a post-streptococcal, autoimmune, neuropsychiatric, movement disorder. There is no effective treatment. In a randomized study, comparison was made of the outcomes of 10 children treated with standard management alone compared to 10 who received additional intravenous immunoglobulin. The outcomes were assessed using a clinical rating scale, brain single-photon emission computed tomography, and the duration of symptomatic treatment. All three outcome measurement tools found improved outcomes in the group that received intravenous immunoglobulin. |
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