| 猴垂体前叶远侧部P物质免疫反应神经纤维与促甲状腺素、促皮质素免疫反应细胞之间的关系 |
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| 引用本文： | 刘少君,鞠躬. 猴垂体前叶远侧部P物质免疫反应神经纤维与促甲状腺素、促皮质素免疫反应细胞之间的关系[J]. 解剖学报, 1991, 0(2) |
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| 作者姓名： | 刘少君 鞠躬 |
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| 作者单位： | 第四军医大学神经生物学研究室，第四军医大学神经生物学研究室 西安 710032，西安 710032 |
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| 摘 要： | 本文主要研究P物质(substance P,SP)免疫反应神经纤维与猴垂体前叶促甲状腺素(thyroid stimulating hormone,TSH)细胞和促皮质素(ACTH)细胞之间的关系。恒河猴垂体前叶切片分别用抗SP和抗TSH,或抗SP与抗ACTH抗体双标记染色。研究中出现SP免疫反应神经纤维与TSH、ACTH细胞非常接近。结果提示,SP能神经纤维可能直接支配TSH或ACTH细胞,并可能参与其分泌的调节。
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| 关 键 词： | 垂体 神经支配 P物质 促甲状腺素 促皮质素 猴 |
THE RELATIONSHIP OF SUBSTANCE P-IMMUNOREACTIVE NERVE FIBERS TO THYROTROPES AND CORTICOTROPES IN THE PARS DISTALIS OF THE ANTERIOR PITUITARY IN THE MONKEY |
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| Liu Shaojun,Ju Gong. THE RELATIONSHIP OF SUBSTANCE P-IMMUNOREACTIVE NERVE FIBERS TO THYROTROPES AND CORTICOTROPES IN THE PARS DISTALIS OF THE ANTERIOR PITUITARY IN THE MONKEY[J]. Acta Anatomica Sinica, 1991, 0(2) |
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| Authors: | Liu Shaojun Ju Gong |
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| Abstract: | In our previous studies substance P-immunoreactive nerve fibers have been demonstrated in the pars distalis of the anterior pituitary in macaque monkeys, and they have been found to contact with somatotropes. The present study investigated the relationship of the substance P immunoreactive fibers to thyrotropes and corticotropes. Macaca mulatta monkeys were used. Sections of the anterior pituitary were double immunostained with antisera against either substance P and human thyroid stimulating hormone or substance P and human ACTH. Substance P immunoreactive varicosities were found to be in close proximity to thyrotropes and corticotropes. It is therefore suggested that a direct neural factor may take part in the regulation of TSH and ACTH secretion |
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| Keywords: | Pituitary Innervation Substance P Thyrotrope Corticotrope Monkey |
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