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连云港地区2726例支原体感染及药敏情况
引用本文:杨英杰,谈笑. 连云港地区2726例支原体感染及药敏情况[J]. 蚌埠医学院学报, 2018, 43(3): 304-306. DOI: 10.13898/j.cnki.issn.1000-2200.2018.03.007
作者姓名:杨英杰  谈笑
作者单位:蚌埠医学院附属连云港市东方医院 皮肤科, 江苏 连云港 222000
摘    要:目的:研究连云港地区支原体感染及药物敏感情况。方法:收集疑为泌尿生殖道感染的2 726例病人的支原体培养及药敏试验结果进行回顾性分析。结果:2 726例受检对象中,支原体感染1 226例(44.97%),其中解脲脲原体(UU)阳性病人995例(81.16%),人型支原体(MH)阳性病人30例(2.45%),UU+MH混合阳性病人201例(16.39%)。女性支原体感染阳性率(54.54%),高于男性(26.48%)(P<0.01)。UU 阳性病人对美满霉素、强力霉素、克拉霉素最为敏感,MH 阳性病人对交沙霉素、强力霉素、美满霉素最为敏感,UU+MH 混合感染病人对美满霉素、强力霉素最为敏感。结论:支原体对部分抗菌药物都产生了不同程度的耐药性,连云港地区支原体感染以UU 为主,其次是UU 和MH 混合感染,治疗上可首选美满霉素、强力霉素治疗。

关 键 词:支原体感染   敏感性   耐药性
收稿时间:2017-10-20

The mycoplasma infection and drug sensitive situation of 2726 cases in Lianyungang
YANG Ying-jie,TAN Xiao. The mycoplasma infection and drug sensitive situation of 2726 cases in Lianyungang[J]. Journal of Bengbu Medical College, 2018, 43(3): 304-306. DOI: 10.13898/j.cnki.issn.1000-2200.2018.03.007
Authors:YANG Ying-jie  TAN Xiao
Affiliation:Department of Dermatology, Lianyungang Oriental Hospital Affiliated to Bengbu Medical College, Lianyungang Jiangsu 222000, China
Abstract:Objective:To investigate the mycoplasma infection status and drug sensitive situation in Lianyungang so as to provide the theoretical basis for clinical rational treatment. Methods:The clinical data of the culture and drug sensitivity of mycoplasma in 2726 cases suspected by urogenital infection were retrospectively analyzed. Results:Among 2726 patients,the mycoplasma infection in 1226 cases(44. 97%) were identified,which included the 995 cases(81. 16%) of the positive UU infection,30 cases(2. 45%) of positive MH infection and 201 cases(16. 39%) of mixed infection. The mycoplasma infection rate in females(54. 54%) was higher than that in males(26. 48%) (P <0. 01). The patients with positive UU infection were mostly sensitive to the minocycline,doxycycline and clarithromycin,and the patients with positive Mh were mostly sensitive to clarithromycin,minocycline and doxycycline,and the patients with mixed UU with MH were mostly sensitive to the minocycline and doxycycline. Conclusions:Mycoplasma is resistant to part of the antimicrobial drug. UU is the major pathogen of mycoplasma infection, followed by mixed UU with MH in Lianyungang, and the minocycline and doxycycline may be the first line drug in treating mycoplasma infection. Drug sensitivity test should be carried out in clinical practice to reduce empiric drug use.
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