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Haemorrhagic pituitary tumours
Authors:C M Lazaro  W Y Guo  M Sami  T Hindmarsh  K Ericson  A L Hulting  J Wersäll
Institution:(1) Department of Neuroradiology, Karolinska Sjukhuset, S-104 01 Stockholm, Sweden;(2) Department of Endocrinology, Karolinska Sjukhuset, Stockholm, Sweden;(3) Department of Oto-Rhino-Laryngology, Karolinska Sjukhuset, Stockholm, Sweden;(4) Department of Radiology, Philippine General Hospital, Manila, Philippines
Abstract:In a group of 69 patients with pituitary tumours, 12 were found to have evidence of intratumoral haemorrhage on MRI, characterized by high signal intensity on short TR/TE sequences. This was verified in all but 1 patient. The majority of the bleedings occurred in macroadenomas. Five (42%) were prolactinomas and 4 (33%) were non-functioning adenomas. There were 2 GH- and 1 ACTH-secreting tumours. All 5 patients with prolactinomas were on bromocriptine medication. Two of the patients had a clinical picture of pituitary apoplexy. The haemorrhage was not large enough to prompt surgery in any of the patients. However, surgical verification of the diagnosis was obtained in 5 cases, while 6 patients were examined with follow-up MRI.
Keywords:Pituitary tumour  Haemorrhage  Magnetic resonance imaging  Bromocriptine medication
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