| 肝纤维化血清学诊断谱的建立及其对肝纤维化的诊断与疗效评价 |
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| 引用本文： | 孙自勤 王要军. 肝纤维化血清学诊断谱的建立及其对肝纤维化的诊断与疗效评价[J]. 滨州医学院学报, 1998, 21(5): 420-423 |
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| 作者姓名： | 孙自勤 王要军 |
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| 作者单位： | 济南军区总医院消化科 |
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| 摘 要： | 目的：建立肝纤维化血清学诊断谱，并探讨其在肝纤维化诊断与疗效考核中的意义。方法：用四氯化碳诱导大鼠产生肝纤维化动物模型，动脉测定多种血清学指标。经筛选，确定血清有机膦酸酯酶，一氧化氮，Ⅲ型前胶原与透明质酸四种指标为联合检测谱。在此基础上，测定了１７１例急，慢性肝病患者这四种指标的变化。结果；随着肝纤维化程度的加深，这些血清学民相应逐渐升高，四种指标联合检测的敏感性为９６％－９８％，特异性为８９％。
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| 关 键 词： | 肝纤维化 血清学标志物 联合检测谱 诊断 |
ESTABLISHMENT OF A SERUM DIAGNOSTIC PROCEDURE AND ITS EXPERIMENTAL AND CLINICAL STUDY FOR THE DIAGNOSIS AND CURATIVE EFFECT ASSESSMENT OF HEPATIC FIBROSIS |
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| Sun Ziqin,Wang Yaojun,Quan Qizhen,et al. ESTABLISHMENT OF A SERUM DIAGNOSTIC PROCEDURE AND ITS EXPERIMENTAL AND CLINICAL STUDY FOR THE DIAGNOSIS AND CURATIVE EFFECT ASSESSMENT OF HEPATIC FIBROSIS[J]. Journal of Binzhou Medical College, 1998, 21(5): 420-423 |
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| Authors: | Sun Ziqin Wang Yaojun Quan Qizhen et al |
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| Abstract: | |
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| Keywords: | hepatic fibrosis combined measurements diagnosis serology curative effect assessment |
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