吸烟和缺碘对育龄妇女血硒、血铅和血镉含量的联合作用

采用2×2析因分析和石墨炉原子吸收仪测定，发现 缺碘(ID)育龄女性吸烟者(SI)全血硒和铅镉有毒元素含量有 明显的交互影响(P均＜0.01)，血液Se含量26.5±8.09μg/L， 明显低于对照(34.2±7.64μg/LPb143.7±2.34μg/L和Cd 10.5±4.83μg/L明显高于对照(97.6±21.7μg/L和3.8± 2.34μg/L。SI单因素亦见有使Se含量减低和Pb、Cd含量增 高的现象ID单因素仅见有Pb含量增高(P＜0.01)。提示SI 和ID共存时对人体内微量元素的吸收和贮存有抑制作用，同 时二者共存时可促进有毒元素Pb和Cd的吸收。该ID流行 区人群的Pb含量增高，与地处交通线，受汽车尾气排放铅尘污 染，造成Pb高本底的可能亦不能排除。

The Joint Actions of Smoke Inhalation and Iodine Deficiency to Childbearing Women's Blood Selenium, Lead and Cadmium Con- tents

The study which adopted 2 × 2 factor-factorial design princi- ple and graphite oven atomic absorptiometer shows that the changes of contents of the toxic elements such like Selenium(Se), Lead(Pb) and Cadmiun(Cd) in women with iodine deficiency (ID) and smoke inhalation ( SI ) have distinct mutual effect ( Pav ＜ 0.01 ). The blood Se' s content was 26.5 ± 8.09μg/L, which obvi- ously lower than that of the control(34.2 ± 7.64μg/L) ;Pb was 143.7 ±-2.34μg/L and Cd was 10.5 ± 4.83μxg/L, which obvious- ly higher than the control(97.6 ± 21.7μg/L and 3.8 ± 2.34μg/ L). The increase of Se and the decrease of Pb and Cd can be seen with SI single factor, but with ID factor only the increase of Pb can be seen (P ＜ 0.01 ). The results showed that the joint action effects of ID and SI inhibit the absorb and store of trace element inside the human body, in the same time, the coexist of ID and SI can promote the absorb of the toxic elements: Pb and Cd. The pop- ulation in the ID epidemic area with high Pb content of cause can not rule out the possibility that it is located in communication lines, the effect of automobile' s tail gas which promote the lead dust's pollution and make the high Pb background.