93例外来建设者真菌性食管炎临床分析

目的了解不同性别、年龄外来建设者真菌性食管炎的发病情况。方法2006~2008年于接受常规电子胃镜检查的15 100例外来建设者为研究对象,分析各年龄、性别组人群真菌性食管炎发病情况,经内镜下刷检涂片染色找到真菌菌丝、孢子确诊为真菌性食管炎。结果15 100例患者中93例(0.62%)检出真菌性食管炎,其中男性65例(0.76%),女性28例(0.43%),性别间检出率差异有统计学意义(P0.05);以10年区分年龄段,男女性真菌性食管炎检出率均随年龄的增加而增长,40岁患者的真菌性食管炎检出率显著高于40岁患者,分别为1.25%和0.50%差异有统计学意义,(P0.005),但在女性却不同,其各相邻年龄组的检出率间差异均无统计学意义;疫情分级:1级29例(31.18%),2级52例(55.91%),3级12例(12.90%);胃镜下伴有消化性溃疡者20例(21.55%)、糜烂性胃炎者12例(12.90%)、食管癌高度可疑者2例(2.2%);抗真菌治疗的反应及预后良好。结论真菌性食管炎发病随年龄增加而升高,男性高于女性;其发病因素为应用抗菌药物、非甾体类消炎药、免疫抑制剂或免疫功能低下、高血糖、食管黏膜屏障破坏等。

Mycotic Esophagitis among 93 Nonnative Workers:A Clinical Analysis

OBJECTIVE To investigate the incidence of mycotic esophagitis among nonnative workers of differrent gender and age.METHODS The incidence of mycotic esophagitis of each sex group and each age subgroup among 15 100 nonnative worker patients who were undergone gastroscopy and esophageal brush smear microscopic examination for candida in our hospital during 2006-2008 was analyzed.RESULTS Ninety-three of 15 100 patients were detectedout mycotic esophagitis(the positive rate was 0.62%).There was siganificant diff...