骨肉瘤治疗进展

骨肉瘤是临床最常见的骨恶性肿瘤。骨肉瘤病理确诊后需要即刻进行放化治疗，截肢手术则作为传统切除肿瘤组织的重要方法，该方式对病情起到了较好的控制效果，但对患者的身心伤害较大，严重影响术后生存质量。随着骨肉瘤发病机制的深入研究，针对该病的治疗也取得了较大的进展，保肢治疗成为当前主要治疗方式，具体方法包括手术联合化疗、分子靶向治疗、免疫治疗和基因治疗等，上述方案改善了部分骨肉瘤的治疗效果，减少术后痛苦，提高术后生存率，具有广泛的应用前景。本文对近10年有关该病的治疗进展进行了总结，现将其综述如下。

Advances in the treatment of osteosarcoma

Osteosarcoma is the most common clinical bone malignant tumor.After the pathological diagnosis of osteosarcoma, it is requiremnt for patients to receive chemoradiotherapy treatment. Amputation is a traditional method to remove the tumor tissue, which can play a good control effect for the state of an illness, but do harm to physical and psychological to seriously affect the quality of life after surgery. With the in-depth study of the mechanism of osteosarcoma, the treatment of osteosarcoma has made great progress. Limb salvage surgery is currently the main treatment of the disease, including surgery combined with chemotherapy, molecular targeted therapy, immunotherapy, gene therapy and so on. The programs will improve efficacy of some patients with osteosarcoma, whch reduce postoperative pain and improve survival rates, with a wide range of applications. In this paper, the progress of the past 10 years about the treatment of osteosarcoma are summarized. Now they all were reviewed as follows.