| 抗癫痫药基因多态性研究进展 |
| |
| 引用本文： | 高森.抗癫痫药基因多态性研究进展[J].中国科学美容,2014(5):59-61. |
| |
| 作者姓名： | 高森 |
| |
| 作者单位： | 天津医科大学总医院,天津300052 |
| |
| 摘 要： | 临床医学上一致认为药物的基因多态性对于抗癫痫药的个体差异有着重要的意义，基因多态性导致个体出现不同的药理和毒理作用。遗传药理学是一门遗传学学科，随着人们对遗传药理学的深入研究，个体化用药有了新的局面。本文首先分析了抗癫痫药的种类及其疗效，然后详细介绍了当前基因多态性对抗癫痫药疗效研究进展。
|
| 关 键 词： | 抗癫痫药 基因多态性 疗效 药物代谢 不良反应 |
Research on genetic polymorphism of antiepileptic drugs |
| |
| GAO Sen.Research on genetic polymorphism of antiepileptic drugs[J].China Scientific Cosmetology,2014(5):59-61. |
| |
| Authors: | GAO Sen |
| |
| Institution: | GAO Sen( Tianjin Medical University General Hospital,Tianjin 300052, China) |
| |
| Abstract: | Clinical agrees that drug＇s gene polymorphism has important meaning for individual differences of antiepileptic drugs, gene polymorphism leads individuals appear different pharmacological and toxicological effects. Pharmacogenetics is a genetics discipline, along with in-depth study of pharmacogenetics, personalized medicine has a new situation. This paper firstly analyzes the types and the effect of antiepileptic drugs, then discusse gene polymorphism on epilepsy medicine clinical research progress. |
| |
| Keywords: | Antiepileptic drugs Gene polymorphism Efficacy Drug metabolism Adverse reaction |
| 本文献已被 维普 等数据库收录！ |
