脑梗死患者颈动脉斑块及其与妊娠相关血浆蛋白A的关系

目的研究颈动脉粥样硬化斑块与脑梗死及妊娠相关血浆蛋白A的关系。方法应用VOIUSON 730彩色超声诊断仪对215例急性脑梗死患者进行颈动脉超声检查，比较脑梗死组和非脑梗死组斑块发生情况，并将患者的病史、个人史及妊娠相关血浆蛋白A与颈动脉粥样硬化的关系进行多因素分析。结果脑梗死组颈动脉粥样硬化斑块检出数较非脑梗死组多，且软斑比率较非脑梗死组高（P〈0．05），分析显示妊娠相关血浆蛋白A是影响脑梗死患者颈动脉粥样硬化斑块的危险因素。结论劲动脉粥样硬化斑块与脑梗死有着密切关系，妊娠相关血浆蛋白A水平可能反映预动脉粥样硬化存在的风险。

Carotid Plaque in Patients with Cerebral Infarction and the Relationship between It and Pregnancy Associated Plasma Protein A

Objective] To study the relationship between atherosclerotic plaque and cerebral infarction, and the relationship between it and pregnancy associatedplasma protein A. Methods ] Carotid ultrasound was performed in 215 patients with acute cerebral infarction by VOIUSON 730 color ultrasonography. The plaque occurrence conditions of cerebral infarction group and non-cerebral infarction group were compared. The relationship between disease history, personal history, pregnancy associated plasma protein A and carotid atherosclerosis was analyzed by multivariate analysis. Results] The detected number of carotid atherosclerotic plaque in cerebral infarction group was more than that in non-cerebral infarction group and the soft plaque rate of cerebral infarction group was higher than that of non-cerebral infarction group （ P 〈 0.05 ）. The analysis result indicated that pregnancy associated plasma protein A was the influencing factor of carotid atherosclerotic plaque in patients with cerebral infarction. Conclusion ] There is a close relationship between carotid atherosclerotic plaque and cerebral infarction, the level of pregnancy associated plasma protein A may reflect the existing risk of carotid atherosclerotic plaque.