Healing of severe ulcerative necrobiosis lipoidica with cyclosporin |
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Authors: | Stanway Amy Rademaker Marius Newman Paul |
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Institution: | Department of Dermatology, Waikato Hospital, Pembroke Street, Private Bag 2500, Hamilton, New Zealand. malc-amy@ihug.co.nz |
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Abstract: | A 55-year-old woman with severe, chronic, treatment-resistant ulcerating necrobiosis lipoidica of the shins was commenced on oral cyclosporin at a dose of 2.5 mg/kg/day. Improvement started within 1 week of commencing treatment, and the lesions healed completely over 8 months. Further ulceration occurred 3 months after discontinuing cyclosporin, with improvement on reintroduction of cyclosporin. There have been four previous case reports of healing of treatment-resistant ulcerating necrobiosis lipoidica with cyclosporin. |
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Keywords: | ulcer |
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