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复方聚乙二醇电解质散用于肠道清洁准备的效果观察
引用本文:杨泽成,;李沫,;刘奇,;张海山.复方聚乙二醇电解质散用于肠道清洁准备的效果观察[J].中国药房,2009(11):853-855.
作者姓名:杨泽成  ;李沫  ;刘奇  ;张海山
作者单位:[1]吉林大学第二临床医学院普通外科疾病诊疗中心,长春市130033; [2]吉林大学中日联谊医院肛肠外科,长春市130033; [3]吉林大学中日联谊医院胃肠外科,长春市130033
摘    要:目的:观察复方聚乙二醇电解质散用于肠道清洁准备的效果。方法:178例拟进行肠道清洁准备的患者,随机分成试验组(使用复方聚乙二醇电解质散)与对照组(使用甘露醇),比较2组肠道清洁度、不良反应和依从性。结果:试验组与对照组的肠道清洁度有效率分别为100.0%、94.2%(P>0.0.05),不良反应发生率分别为8.7%、27.9%(P<0.05),完全依从率分别为96.7%、80.2%(P<0.05)。结论:复方聚乙二醇电解质散用于肠道清洁准备效果好,不良反应少,患者依从性高,适合临床推广应用。

关 键 词:甘露醇  复方聚乙二醇电解质散  肠道准备

Efficacy of Polyethylene Glycol - Electrolyte Powder for Bowel Preparation
Institution:YANG Ze-cheng,LI Mo, ZHANG Hai-shan,LIU Qi(1.Center for Cure and Diagnosis of Diseases of General Surgery, Jilin University Second Hospital, Changchun 130033, China;2.Dept. of Anorectal Surgery, China- Japan Union Hospital of Jilin University, Changchun 130033, China;3.Dept. of Gastrointestinal Surgery, China- Japan Union Hospital of Jilin University, Changchun 130033, China)
Abstract:OBJECTIVE: To evaluate the efficacy of polyethylene glycol electrolyte powder for bowel preparation. METHODS: 178 patients who were expected to undergo bowel preparation were randomized to either trial group (treated with polyethylene glycolelectrolyte powder) or control group (with mannitol) . Colon cleanliness, adverse reactions and patients' compliances were compared between the two groups. RESULTS: In trial group versus control group, the bowel cleanliness effective rate was 100.0% vs. 94.2% (P 〉0.05); the incidence of adverse reactions was 8.7% vs. 27.9 % (P 〈 0.05), and the complete compliance rate was 96.7% vs. 80.2% (P〈0.05) . CONCLUSION: Polyethylene glycol electrolyte powder is effective for bowel preparation yet with few adverse reactions, and to which patients' showed good compliance, which thus deserves to be widely used in clinical practice.
Keywords:Mannitol  Polyethylene glycol- electrolyte powder  Bowel preparation
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