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尼莫地平治疗脑出血的疗效观察
引用本文:贺歆彦,吴大鸿,熊劲,吴立新.尼莫地平治疗脑出血的疗效观察[J].中国药房,2009(11):852-853.
作者姓名:贺歆彦  吴大鸿  熊劲  吴立新
作者单位:贵州黔南州人民医院神经内科,都匀市558000
摘    要:目的:观察尼莫地平治疗脑出血的疗效。方法:60例脑出血患者随机分为治疗组与对照组。对照组给予常规治疗,治疗组在常规治疗的基础上给予尼莫地平治疗14 d。治疗前、治疗14 d进行神经功能缺损评分及疗效评定。结果:治疗14 d时,治疗组神经功能缺损评分为13.6±8.1,明显低于对照组的17.8±8.3(P<0.05);治疗组有效率83.3%,明显高于对照组的56.7%(P< 0.05)。结论:尼莫地平治疗脑出血疗效好,可减轻脑水肿,保护神经细胞,改善患者的神经功能。

关 键 词:尼莫地平  脑出血  脑水肿

Clinical Efficacy of Nimodipine for Cerebral Hemorrhage
HE Xin-yan,WU Da-hong,XIONG Jin,WU Li-xin.Clinical Efficacy of Nimodipine for Cerebral Hemorrhage[J].China Pharmacy,2009(11):852-853.
Authors:HE Xin-yan  WU Da-hong  XIONG Jin  WU Li-xin
Institution:(Dept. of Neurology, Guizhou Qiannan State People' s Hospital, Duyun 558000, China)
Abstract:OBJECTIVE: To observe the clinical efficacy of Nimodipine for patients with cerebral hemorrhage. METHODS: A total of 60 patients with cerebral hemorrhage were randomly divided into treatment group and control group. The treatment group were given nimodipine plus the routine therapy while the control group received routine therapy alone. The clinical neurologic impairment scores (CCS) and clinical effects of two groups were observed before treatment and at 14 days after treatment. RESULTS: At 14 days after treatment, the neurologic impairment score (CCS) in the treatment group was significantly lower than in the control group (13.6±8.1 vs. 17.8± 8.3, P〈0.05) but the clinical effective rate was signifi- cantly higher than in the control group (83.3% vs 56.7%, P〈0.05). CONCLUSION: Nimodipine showed satisfactory clinical efficacy for cerebral hemorrhage in that it relieved cerebral edema, protected the neural cells and improved the neurologic function of patients with cerebral hemorrhage.
Keywords:Nimodipine  Cerebral hemorrhage  Cerebral edema
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