| 狗总胆管结扎所致肝硬化门脉高压症的肝脏血流动力学改变 |
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| 引用本文： | 赵秋,但自力,李绍白.狗总胆管结扎所致肝硬化门脉高压症的肝脏血流动力学改变[J].华中科技大学学报(医学版),1990(4). |
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| 作者姓名： | 赵秋 但自力 李绍白 |
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| 作者单位： | 广州军区武汉总医院消化内科
(赵秋)，同济医科大学肝病研究所
(但自力)，同济医科大学肝病研究所(李绍白) |
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| 摘 要： | 本实验通过自身对照研究探讨狗总胆管结扎(CBDL)所致肝硬化门脉高压症的肝脏血流动力学的特征,结果表明:狗总胆管结扎后门静脉压力、嵌塞肝静脉压力、门-腔静脉压力梯度均较结扎前明显增加,门静脉血流量明显减少,而肝动脉血流量明显增加。门静脉血管阻力明显增加,而肝动脉血管阻力明显降低。肝脏组织学检查显示为完全和(或)不完全分隔型纤维间隔形成。上述改变与人类肝硬化门脉高压所见者一致。
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| 关 键 词： | 血液动力学 门脉高压症 总胆管结扎 |
The Hemodynamic Characterization of Cirrhotic Portal Hypertention Induced by Common Bile Duct Ligation in Dogs |
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| Zhao Qiu,Dan Zili,Li Shaobai Institute of Liver Disease,Tongji Medical University,Wuhan.The Hemodynamic Characterization of Cirrhotic Portal Hypertention Induced by Common Bile Duct Ligation in Dogs[J].Journal of Huazhong University of Science and Technology(Health Sciences),1990(4). |
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| Authors: | Zhao Qiu Dan Zili Li Shaobai Institute of Liver Disease Tongji Medical University Wuhan |
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| Abstract: | The purpose of this experimental study is to explore the hemodyna-mic characterization of portal hypertention induced by common bile duct liga-tion(CBDL) in dogs.The experimental result suggests that the hemodynamic characterization of portal hypertention induced by CBDL in dogs very markedly resembles that of cirrhotic portal hypertention in man,with increase in portal venous pressure,wedged hepatic venous pressure,portal venous vascular resistence,hepatic artery inflow and decrease in portal venous inflow,hepatic artery vascular resistence |
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| Keywords: | hemodynamics portal hypertension common bile duct ligation |
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