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Pharmacokinetics of prolonged‐release tacrolimus versus immediate‐release tacrolimus in de novo liver transplantation: A randomized phase III substudy
Authors:Bo‐Göran Ericzon  Evaristo Varo  Pavel Trunečka  Lutz Fischer  Michele Colledan  Bruno Gridelli  Andrés Valdivieso  John O'Grady  James Dickinson  Nasrullah Undre
Affiliation:1. Division of Transplantation Surgery, Karolinska University Hospital Huddinge, Stockholm, Sweden;2. Liver Transplant Unit, University Hospital Santiago de Compostela, Santiago de Compostela, Spain;3. Transplantcentre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic;4. Department of Hepatobiliary and Transplant Surgery, University Medical Center, Hamburg‐Eppendorf, Germany;5. Department of Surgery, Ospedale Giovanni XXIII, Bergamo, Italy;6. Division of Abdominal and Transplantation Surgery, ISMETT, Palermo, Italy;7. Liver Transplant Unit, Cruces University Hospital, Baracaldo‐Bilbao, Spain;8. Liver Transplant Unit, King's College Hospital, London, UK;9. Clinical Services, NUVISAN GmbH, Neu‐Ulm, Germany;10. Medical affairs, Astellas Pharma Europe Ltd, Chertsey, UK
Abstract:
Keywords:calcineurin inhibitor  immunosuppressant  liver transplantation  living donor  pharmacokinetics/pharmacodynamics  rejection  tacrolimus
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