Symmetrical peripheral gangrene: association with noradrenaline administration |
| |
Authors: | M A Hayes E H S Yau C J Hinds J D Watson MD |
| |
Institution: | (1) Department of Anaesthesia, St. Bartholomew's Hospital, ECIA 7 BE London, UK;(2) Department of Intensive Care, St. Bartholomew's Hospital, ECIA 7 BE London, UK;(3) Homerton Hospital, ECIA 7 BE London, UK |
| |
Abstract: | The syndrome of symmetrical peripheral gangrene is characterised by distal ischaemic damage in two or more extremities, without large vessel obstruction. Four patients with bilateral pedal ischaemia are described and their haemodynamic profiles presented. In all four cases the syndrome developed in association with noradrenaline administration, sepsis and DIC, despite a high cardiac output and a low calculated systemic vascular resistance index. Early treatment with epoprostenol was instituted in the final case and was successful. |
| |
Keywords: | Gangrene disseminated intravascular coagulation Epoprostenol |
本文献已被 SpringerLink 等数据库收录! |
|