| 植物活性多糖抗癌活性的研究——抗自由基作用 |
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| 引用本文： | 陈磐,陈绍瑗,冯懿挺,傅承新. 植物活性多糖抗癌活性的研究——抗自由基作用[J]. 中国药物与临床, 2004, 4(8): 606-608 |
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| 作者姓名： | 陈磐 陈绍瑗 冯懿挺 傅承新 |
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| 作者单位： | 浙江大学生命科学学院生物科学系,310029 |
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| 摘 要： | 目的研究当归、鬼臼、黄芪和猫人参多糖对羟自由基的清除作用。方法采用分光光度法测定羟自由基清除率。结果半数抑制浓度(IC50)分别为当归0.4040g/L、鬼臼0.1021g/L、黄芪0.08782g/L和猫人参0.4913g/L。结论4种多糖对羟自由基的清除能力大小依次为黄芪>鬼臼>当归>猫人参,一定浓度范围内清除作用与多糖浓度具有正相关性。
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| 关 键 词： | 羟自由基 植物多糖 抗自由基 |
| 修稿时间： | 2004-05-16 |
Anticancer effect of plant polysaccharides-hydroxy radical scavenging activities |
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| CHEN Pan,CHEN Shao-yuan,FENG Yi-ting,FU Cheng-xin. Anticancer effect of plant polysaccharides-hydroxy radical scavenging activities[J]. Chinese Remedies & Clinics, 2004, 4(8): 606-608 |
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| Authors: | CHEN Pan CHEN Shao-yuan FENG Yi-ting FU Cheng-xin |
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| Affiliation: | CHEN Pan,CHEN Shao-yuan,FENG Yi-ting,FU Cheng-xin. Department of Biology,Life Science College of Zhejiang University,Hangzhou 310029,China |
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| Abstract: | Objective To investigate the clearing effect on hydroxy radical by Angelica polysaccharide (AnPS), Podophyllum polysaccharide (PPS), Astragalus polysaccharide (AsPS) and Actinidia polysaccharide(AcPS). Method Clearance rate is quantitated by spectrophotometry. Result IC50 of AnPS, PPS, AsPS and AcPS were 0.4040, 0.087 82, 0.1021 and 0.4913 g/L respectively. Conclusion There is a positive correlation between the clearing-rate and polysaccharide concentration. |
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| Keywords: | Hydroxy radical Plant polysaccharide Antiradical |
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