| 气相色谱法测定八宝散中龙脑的含量 |
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| 引用本文： | 李思华,张健泓,侯伟雄.气相色谱法测定八宝散中龙脑的含量[J].中国药业,2009,18(21):30-31. |
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| 作者姓名： | 李思华 张健泓 侯伟雄 |
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| 作者单位： | 1. 广东省人民医院药学部,广东广州,510080
2. 广东食品药品职业学院,广东广州,510520 |
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| 摘 要： | 目的建立测定八宝散中龙脑含量的气相色谱法。方法以水杨酸甲酯为内标，色谱柱为DB-1毛细管柱（30m×0．25mm，0．25μm），采用FID检测器，程序升温（初始温度80℃，停留1min，然后以8℃／min升至180℃），载气为高纯氦气，流速1mL／min。结果龙脑质量浓度在0．3018～2．012g／L范围内与峰面积线性关系良好，平均加样回收率为97．35％，RSD为1．02％（n=6）。结论HPLC法方便、准确，重现性好，可作为龙脑的质量控制方法。
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| 关 键 词： | 八宝散 气相色谱法 龙脑 含量测定 |
Quantitative Determination of Borneol in Babao Powder by GC-FID |
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| Li Sihua,Zhang Jianhong,Hou Weixiong.Quantitative Determination of Borneol in Babao Powder by GC-FID[J].China Pharmaceuticals,2009,18(21):30-31. |
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| Authors: | Li Sihua Zhang Jianhong Hou Weixiong |
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| Institution: | 1. Pharmaceutical Department of Guangdong Provincial People＇s Hospital, Guangzhou, Guangdong, China 510080; 2. Guangdong Food and Drug Vocational College, Guangzhou, Guangdong, China 510520) |
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| Abstract: | Objective To establish a GC method for determining the content of borneol in Babao Powder. Methods Using methyl salicylate as the internal standard, the content of borneol was assayed by DB-1 capillary column（30 m ×0. 25 mm, 0.25μm） with FID detector and programmed temperature, in which the temperature was promoted by 8℃/min to 180℃ at the initial temperature of 80℃ remaining 1 min, using higher pure helium as the carrier gas. The flow rate was 1 mL/min. Results The standard curve of borneol was linear over the range of 0. 301 8 - 2. 012 g/L. The average recovery rate of the adding sample was 97.35%, RSD was 1.02% （ n = 6）. Conclusion This method is simple, accurate and reproducible. It can be reliable for the quality control of Babao Powder. |
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| Keywords: | Babao Powder GC bomeol content determination |
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