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艾司洛尔对气管插管应激反应的影响
引用本文:操隆辉,周建华,曾维安,林文前. 艾司洛尔对气管插管应激反应的影响[J]. 岭南急诊医学杂志, 2007, 12(6): 431-432,439
作者姓名:操隆辉  周建华  曾维安  林文前
作者单位:华南肿瘤学国家重点实验室,中山大学肿瘤防治中心麻醉科,510060;华南肿瘤学国家重点实验室,中山大学肿瘤防治中心超声科,510060
摘    要:目的:探讨艾司洛尔对气管插管应激反应的影响。方法:选择全麻下非心脏手术患者60例,随机分为生理盐水组(C组)和艾司洛尔组(E组)各30例。观察两组患者全麻诱导前,予以艾司洛尔或生理盐水前的基础值,及插管前,插管时,插管后1min,3min,5min的无创血压、心率及心输出量的变化。结果:在气管插管后,C组患者的平均动脉压、心率、心输出量上升的幅度均明显大于E组(P〈0.05)。结论:艾司洛尔可以抑制气管插管应激反应。

关 键 词:艾司洛尔  气管插管  应激反应
修稿时间:2007-07-28

Effect of Esmolol on the Stress Response to Intubation
CAO Long-hui,ZHOU Jian-hua,ZENG Wei-an,LIN Wen-qian. Effect of Esmolol on the Stress Response to Intubation[J]. Lingnan Journal of Emergency Medicine, 2007, 12(6): 431-432,439
Authors:CAO Long-hui  ZHOU Jian-hua  ZENG Wei-an  LIN Wen-qian
Affiliation:CAO Long-hui, ZHOU Jian-hua, ZENG Wei-an, LIN Wen-qian( 1. Department of Anesthesiology, Cancer Center, Sun Yat-sen University, State Key Laboratory of Oncology in South China, Guangzhou, 510060 ;2. Department of ultrasound)
Abstract:Objective: To explore the effect of esmolol on the stress response to intubation. Methods: Sixty patients scheduled for elective non-cardiac surgery were randomly divided into two groups (Group E and C), 30 for each. In each group, MAP, HR and CO were recorded at preinduction, before the administration of esmolol or saline (baseline), preintubation, intubation and 1min, 3min, 5min after intubation. Results: After intubation, MAP, HR and CO all increased in two groups, but the average maximum of group C increase is significantly higher than group E (P < 0.05). Conclusion: Esmolol can suppress the stress response to intubation.
Keywords:esmolol  intubation  stress response
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