扶正通脉胶囊治疗急性期脑梗死51例临床观察

目的观察扶正通脉胶囊治疗急性期脑梗死的临床疗效,并研究其作用机制.方法选择81例符合中医辨证属气虚血瘀、痰阻络痹并经头颅CT确诊为急性期脑梗死的病人,随机分为治疗组(51例)和对照组(30例).治疗组服用扶正通脉胶囊,对照组服用络欣通,连续治疗28 d观察疗效.结果治疗组总有效率94.12%,对照组总有效率93.33%,两组比较无统计学意义(P>0.05),但治疗组愈显率(74.51%)明显高于对照组(40.00%,P<0.05).病人神经功能缺损恢复程度及血液流变学指标改善等方面,治疗组均优于对照组(P<0.05或P<0.01).服药过程中及服药后未见药物不良反应.结论扶正通脉胶囊对气虚血瘀型、痰阻络痹脑梗死急性期具有良好的治疗效果,并能改善血液流变学指标,降低血液黏稠度,改善脑部症状区血液循环,促进受损脑细胞功能恢复,降低病残率,提高生存质量.

Fuzhengtongmai Capsule for Treatment of Acute Cerebral Infarction

Objective To observe the effect of Fuzhengtongmai(FZTMC) Capsules(FZTMC) on acute cerebral infarction(ACI) with Qi deficiency and blood stasis,phlegm stagnation and collaterals bi(TCM).Methods Eighty-one patients with acute cerebral infarction( Qi deficiency and blood stasis,phlegm stagnation and collaterals bi-syndrome diagnosis by TCM) were divided into two groups randomly: Treatment group(TG,n=51) treated by FZTMC and control group (CG,n=30) treated by Luoxintong for 28 days.Results The total effective rate was 94.12% in the treatment group and 93.33% in the control group respectively(P>0.05).The marked effective and cure rate was higher in TG(74.51%) than that in CG(40.00%). The recovery degree of neurological deficit and the improvement of blood rheology were better in TG than that in CG(P<0.05 or P<0.01). No side-effects were found.Conclusion The results show that FZTMC Could promote the functional recovery of damaged cerebral cells and decrease the disability rate.