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地尔硫治疗合并快速心房颤动的心力衰竭
引用本文:邓兵,罗明,许嘉鸿.地尔硫治疗合并快速心房颤动的心力衰竭[J].中国新药与临床杂志,2001(Z1).
作者姓名:邓兵  罗明  许嘉鸿
作者单位:同济大学附属同济医院心内科 上海200065 (邓兵,罗明),同济大学附属同济医院心内科 上海200065(许嘉鸿)
摘    要:目的 :观察地尔硫对合并快速心房颤动心力衰竭的疗效。方法 :4 2例合并快速心房颤动的心力衰竭病人分为地尔硫组 2 2例 ,硝酸甘油组2 0例 ,除常规治疗外 ,分别给予地尔硫 30mg或硝酸甘油 30mg ,均iv ,gtt,gd× 2wk。采用心功能分级和超声心动图检查左室射血分数 ,评价静脉滴注地尔硫和硝酸甘油的治疗效果。结果 :地尔硫对快速心房颤动心力衰竭治疗的有效率达 86% ,左室射血分数显著增加 ,且较硝酸甘油更明显。结论 :地尔硫对合并快速心房颤动心力衰竭治疗有效 ,不良反应少 ,较硝酸甘油疗效更好。

关 键 词:地尔硫  充血性心力衰竭  心房颤动

Effects of diltiazem on heart failure with atrial fibrillation of rapid ventricular rate
DENG Bing,LUO Ming,XU Jia Hong.Effects of diltiazem on heart failure with atrial fibrillation of rapid ventricular rate[J].Chinese Journal of New Drugs and Clinical Remedies,2001(Z1).
Authors:DENG Bing  LUO Ming  XU Jia Hong
Abstract:AIM: To investigate the effects of diltiazem on heart failure with atrial fibrillation of rapid ventricular rate. METHODS:The forty two patient with heart failure are assosiated with atrial fibrillation of rapid ventricular rate were divided into two groups. Diltiazem group( n =22) and nitroglycarin group. The diltiazem group was treated with diltriazem 30 mg, iv, gtt, qd×2 wk. The nitroglycerin group was treated with nitroglycerin 30 mg iv, gtt, qd×2 wk. The cardiac functional classification and the left ventricular ejection fraction detected by echocardiography were used to evaluate the effects of diltiazem and nitroglycerin. RESULTS:Treatment with diltiazem had high rate of therapeutic efficacy to 86 % on heart failure with atrial fibrillatiion of rapid ventricular rate, and the left ventricular ejection fraction was improved more than that of treatment with nitroglycerin. CONCLUSION: Diltiazem is effective and with few adverse reactions in the treatment of heart failure with atrial fibrillation of rapid ventricular rate, and has better therapeutic efficacy than that of nitroglycerin.
Keywords:diltiazem  congestive heart failure  atrial flutter
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