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钆塞酸二钠增强磁共振成像在肝纤维化分期早期诊断中的临床应用效果
引用本文:李彦龙,王逢茂,李妍,路志伟,刘奔,闫明策,张媛. 钆塞酸二钠增强磁共振成像在肝纤维化分期早期诊断中的临床应用效果[J]. 临床医学研究与实践, 2021, 6(11): 122-124
作者姓名:李彦龙  王逢茂  李妍  路志伟  刘奔  闫明策  张媛
作者单位:延安大学咸阳医院,陕西 咸阳,712000
摘    要:目的 分析钆塞酸二钠(Gd-EOB-DTPA)增强磁共振成像(MRI)在肝纤维化分期早期诊断中的临床应用效果.方法 回顾性分析2019年1月至2020年1月在我院放射科接受Gd-EOB-DTPA增强MRI的130例肝纤维化患者的临床资料,其中118例具有病理组织学资料.采用Gd-EOB-DTPA增强MRI测量患者的左右...

关 键 词:肝纤维化  钆塞酸二钠  磁共振成像

Clinical application effect of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid enhanced magnetic resonance imaging in early diagnosis of hepatic fibrosis staging
LI Yanlong,WANG Fengmao,LI Yan,LU Zhiwei,LIU Ben,YAN Mingce,ZHANG Yuan. Clinical application effect of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid enhanced magnetic resonance imaging in early diagnosis of hepatic fibrosis staging[J]. Clinical Research and Practice, 2021, 6(11): 122-124
Authors:LI Yanlong  WANG Fengmao  LI Yan  LU Zhiwei  LIU Ben  YAN Mingce  ZHANG Yuan
Affiliation:(Xianyang Hospital of Yan'an University,Xianyang 712000,China)
Abstract:Objective To analyze the clinical application effect of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid(Gd-EOB-DTPA)enhanced magnetic resonance imaging(MRI)in early diagnosis of hepatic fibrosis staging.Methods The clinical datas of 130 patients with hepatic fibrosis who received Gd-EOB-DTPA enhanced MRI in the radiology department of our hospital from January 2019 to January 2020 were retrospectively analyzed.Among them,118 patients had histopathological data.Gd-EOB-DTPA enhanced MRI was used to measure the volume ratio of left and right liver lobes(L/R LVR),and the area under receiver operating characteristic(AUROC)of L/R LVR in the diagnosis of liver fibrosis was evaluated.Results There was a positive correlation between L/R LVR and the stage of liver fibrosis(r=0.739,P=0.000),that is,the larger the L/R LVR,the later the stage of liver fibrosis.L/R LVR had certain advantages in staging diagnosis of liver fibrosis[AUROC=0.868,95%CI(0.802-0.934)].Conclusion The L/R LVR measured by Gd-EOB-DTPA enhanced MRI has certain value for the early diagnosis of liver fibrosis stage.
Keywords:hepatic fibrosis  gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid  magnetic resonance imaging
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