Effects of divalent metal ions on the uptake of glutamate and GABA from synaptosomal fractions |
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| Authors: | B. Gabrielsson T. Robson D. Norris S.H. Chung |
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| Affiliation: | 1. Fujian Engineering and Technology Research Center for Comprehensive Utilization of Marine Products Waste, Fuzhou University, Fuzhou, Fujian 350108, China;2. Fuzhou Industrial Technology Innovation Center for High Value Utilization of Marine Products, Fuzhou University, Fuzhou, Fujian 350108, China |
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| Abstract: | The effects of divalent metal ions on high affinity uptake glutamate and GABA were examined, using crude and purified synaptosomal fractions prepared from brains of DBA/2CBI. The uptake velocities of both amino acids are severely reduced in the presence of Cu2+, Fe2+ and Zn2+ but remain unaffected by Co2+. |
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| Keywords: | Metal High affinity uptake Glutamate uptake GABA uptake |
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