| 枸杞多糖的分离纯化及其抗疲劳作用 |
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| 引用本文： | 罗琼,阎俊,张声华.枸杞多糖的分离纯化及其抗疲劳作用[J].卫生研究,2000,29(2):115-117. |
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| 作者姓名： | 罗琼 阎俊 张声华 |
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| 作者单位： | 1. 湖北医科大学卫生学教研室,武汉,430071
2. 华中农业大学食品科学 |
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| 基金项目： | 湖北省自然科学基金! ( No.95 J2 5 ) |
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| 摘 要： | 采用萃取，离子交换层析及凝胶层析枸杞中获得枸杞多糖；将纯化的枸杞多糖（ＬＢＰ－Ｘ）按５，１０，２０，５０及１００ｍｇ．ｋｇ＾－１．ｄ＾－１分别灌喂小鼠，进行抗疲劳实验。结果表明，ＬＢＰ－Ｘ能显著地增加小鼠肌糖后，肝糖原储备量，提高运动前，后血液乳酸脱氢酶总活力；降低小鼠剧烈运动后血尿素氮增加量，加快运动后血尿素氮的清除速率，以ＬＢＰ－Ｘ １０ｍｇ．ｋｇ＾－１．ｄ＾－１剂量组效果最佳。
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| 关 键 词： | 枸杞 纯化 抗疲劳作用 |
| 修稿时间： | 1999-06-23 |
Isolation and purification of lycium barbarum polysaccharides and its antifatigue effect |
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| Luo Qiong,Yan Jun,Zhang Shenghua.Isolation and purification of lycium barbarum polysaccharides and its antifatigue effect[J].Journal of Hygiene Research,2000,29(2):115-117. |
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| Authors: | Luo Qiong Yan Jun Zhang Shenghua |
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| Institution: | Department of Hygiene, Hubei Medical University, Wuhan 430071, China. |
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| Abstract: | A purified component of lycium barbarum polysaccharide (LBP-X) was isolated from lycium barbarum L. by DEAE ion-exchange cellulose and sephacryl gel chromatography. LBP-X was tested on five different doses (5, 10, 20, 50 and 100 mg.kg-1.d-1) in mice. The results showed that LBP-X induced a remarkable adaptability to exercise load, enhanced resistance and accelerated elimination of fatigue. LBP-X could enhance the storage of muscle and liver glycogen, increase the activity of LDH before and after swimming, decrease the increase of blood urea nitrogen (BUN) after strenuous exercise, and accelerate the clearance of BUN after exercise. The dosage of LBP-X 10 mg.kg-1.d-1 was the best amount among the five tested doses. |
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| Keywords: | purified lycium barbarum polysaccharide antifatigue |
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