Abstract: | The reaction of organism to hip replacement was studied in 75 patients. The reaction developed in response to operative intervention either immediately after the operation (within 1-3 months) or to the beginning of the active functioning of the artificial joint (from the 6th month after operation). The development of complications after implantation of the endoprosthesis was followed by certain shifts of immunological indices. Prognostic criteria of the development of the implant instability before operation were a reduced level of immunoglobulin G and higher concentration of immunoglobulin E, in the long term period they are an increased level of IL-1 and of the content of cytoplasm cationic proteins of neutrophils. |