血清胆红素和血脂对冠心病发生的作用 |
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引用本文: | 李现立,郑晓晖,郝增光,杨睿,葛慧敏,Xian-li,Xiao-hui,Zeng-guang,Hui-min.血清胆红素和血脂对冠心病发生的作用[J].中原医刊,2010(4). |
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作者姓名: | 李现立 郑晓晖 郝增光 杨睿 葛慧敏 Xian-li Xiao-hui Zeng-guang Hui-min |
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摘 要: | 目的 探讨血清胆红素和血脂在冠心病发生中的作用.方法 75例冠心病患者被分为高脂血症组(46例)和非高脂血症组(29例),35例正常健康成人作为对照组,分别测定血清总胆红素(TBIL)、直接胆红素(DBIL)、间接胆红素(IBIL)以及总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)水平等指标作对比分析.结果 高脂血症组TBIL、DBIL、IBIL均低于非高脂血症组和正常对照组,差异有统计学意义(P<0.05);非高脂血症组血清胆红素水平低于正常对照组,差异有统计学意义(P<0.05).高脂血症组同非高脂血症组、正常对照组比较,TC、TG和LDL增高,HDL降低,差异有统计学意义(P<0.05);非高脂血症组同正常对照组比较,TC、TG和LDL增高,HDL降低,但差异无统计学意义(P>0.05).结论 低胆红素水平在高脂血症和非高脂血症的冠心病发生中起着重要的作用,是冠心病的独立危险因素.
Abstract:
Objective To investigate the effection of serum bilirubin and serum lipid on coronary heart disease (CHD). Methods Seventy -five patients with CHD group were divided into hyperlipidemia group(46 cases) and non- hyperlipidemia group (29 cases),35 healthy controls (healthy control group)were enrolled in the study. Serum total bilirubin (TBIL), direct bilirubin (DBIL), indirect bilirubin (IBIL)serum triglycride ( TG), total cholestrol ( TC ), low density lipoprotein (LDL), high density lipoprotein (HDLand serum lipid were examined for all subiects,and then the results were compared and analyzed. Results The contents of serum TBIL, direct bilirubin (DBIL), indirect bilirubin (IBIL)were lower in hyperlipidemia group than those of non - hyperlipidemia and healthy control group, the difference was significant (P <0. 05 ). The contents of serum bilirubin were lower in non - hyperlipidemia group than those of healthy control group, the difference was significant( P < 0.05 ). TC,TG and LDL were higher and HDL was lower in hyperlipidemia group than those of healthy control group and non - hyperlipidemia group, the difference was significant( P <0.05). TC,TG and LDL were higher and HDL was lower in non -hyperlipidemia group than those of healthy control group,There was no difference in the two groups( P >0.05). Conclusions The lower serum bilirubin level is an independent risk factor of coronary heart disease in hyperlipidemia and non- hyperlipidemia groups.
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关 键 词: | 血清胆红素 血脂 冠心病患者 coronary heart disease 高脂血症 统计学意义 difference control significant 对照组 serum lipid 胆红素水平 LDL 差异 HDL Results 血清总胆红素 高密度脂蛋白 独立危险因素 低密度脂蛋白 |
Effection of serum bilirubin and serum lipid on coronary heart disease |
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Abstract: | Coronary heart disease Serum bilirubin Serum lipid |
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Keywords: | Coronary heart disease Serum bilirubin Serum lipid |
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