急性冠状动脉综合征不同证候病变血管数、血管狭窄程度、 Braunwald积分比较及相关性研究

目的比较急性冠状动脉综合征 (ACS)患者不同中医证候之间的病变血管数、血管狭窄程度和临床严重程度 (Braunwald积分 ),并探讨其相关性.方法在给 70例 ACS患者作冠状动脉造影之前,进行中医辨证并作反映病情严重程度的 Braunwald计分,记录患者冠状动脉造影所示病变血管数和血管狭窄程度.对不同中医证候间的 Braunwald积分、病变血管数积分和血管狭窄程度积分及其相关性统计处理.结果 70例 ACS患者各中医证候组之间的 Braunwald积分有显著差异,其中阳虚及兼证者最高;而各证候间的病变血管数积分和血管狭窄程度积分相近.患者病变血管数积分、血管狭窄程度积分与临床严重程度 Braunwald积分间亦无相关关系.结论中医临床证候分型较之冠状动脉造影,能更为确切地表现和预测 ACS的临床严重程度和预后.

Study on the Number of Vulnerable Vessels,Level of Coronary Artery Stenosis,Integra of Braunwald Clinical Grades and their Correlation among Different Traditional Chinese Medcine Syndromes in Patients with Acute Coronary Syndromes

Objective:To compare the number of vulnerable vessels,level of coronary artery stenosis,integra of braunwald clinical grades among different Traditional Chinese medicine(TCM) Syndromes in patients with acute coronary syndromes(ACS),and study their correlation. Methods:70 patients with ACS were differentiated their TCM syndromes and counted their integra of braunwald clinical grades before coronary arteriography(CAG),and recorded their scores of number of vulnerable vessels,level of coronary artery stenosis arter CAG,then integra of braunwald clinical grades and scores of number of vulnerable vessels,level of coronary artery stenosis among different TCM syndromes and their correlation were compared statistically. Results:In Yang- Ddeficiency group,the integra of braunwald clinical grades was highest than the other groups,however,there was no significant difference in scores of number of vulnerable vessels,level of coronary artery stenosis among different TCM syndromes,and no significant correlation between integra of braunwald clinical grades and scores of number of vulnerable vessels,level of coronary artery stenosis in 70 patients with ACS. Conclusion:The methods of TCM Syndromes differentiating could reflect clinical severities and prognosis of ACS patients more certainly than coronary arteriography.