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Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models |
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| Authors: | Kevin B. Teuscher Somenath Chowdhury Kenneth M. Meyers Jianhua Tian Jiqing Sai Mayme Van Meveren Taylor M. South John L. Sensintaffar Tyson A. Rietz Soumita Goswami Jing Wang Brian C. Grieb Shelly L. Lorey Gregory C. Howard Qi Liu William J. Moore Gordon M. Stott William P. Tansey Taekyu Lee Stephen W. Fesik |
| Abstract: | |
| Keywords: | WDR5 MYC structure-based design in vivo efficacy cancer therapy |