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Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling
Authors:Jochem Louisse  Sieto Bosgra  Bas J. Blaauboer  Ivonne M. C. M. Rietjens  Miriam Verwei
Affiliation:1. Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE, Wageningen, The Netherlands
2. TNO, PO Box 360, 3700 AJ, Zeist, The Netherlands
3. Institute for Risk Assessment Sciences (IRAS), Utrecht University, PO Box 80176, 3508 TD, Utrecht, The Netherlands
Abstract:
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