脉冲多普勒组织成像定量分析血管重建术前后 左心室局部与整体的收缩功能

目的　采用脉冲多普勒组织成像技术 (PW DTI)定量分析血管重建术前后左心室的收缩功能。方法　 16例健康人 ,2 0例冠心病患者均行 2 DE及DTI。采用PW DTI分析血管重建术前、后左室壁及二尖瓣环DTI指标 :收缩期峰值收缩速度Vs、射血前时间PEP、射血前时间PEP与局部射血时间ET之比PEP/ET、二尖瓣环 4个位点平均收缩速度值Vmva。结果　冠心病患者与健康人比较 ,室壁运动异常节段Vs显著降低 (P <0 .0 1) ,PEP延长 (P <0 .0 5 ) ,PEP/ET值增大 (P <0 .0 1) ;冠心病患者血管重建术前后比较 ,室壁运动恢复节段Vs显著增高 (P <0 .0 1) ,PEP缩短 (P <0 .0 5 )、PEP/ET值减小 (P <0 .0 1) ,血管重建术后Vmva增高 ,且左室射血分数EF与Vmva呈显著正相关 (r=0 .81,P <0 .0 1)。结论　PW DTI可实时监测心肌运动变化情况 ,定量检测血管重建术前后左室局部与整体收缩功能

Quantitively Analysing of Regional and Global Left Ventricular Systolic Function before and after Revascularization by Doppler Tissue Imaging

Objective Pulsed wave Doppler tissue imaging (PWDTI)was used to quantitively analyse left ventricular systolic function before and after revascularization. Methods 2 DE and PWDTI were performed in 20 patients with CAD and 16 healthy controls. PWDTI was also performed after revascularization. PWDTI indexes including Vs, PEP, PEP/ET and Vmva. Results Compared with healthy controls, group of patients with CAD had significantly reduced Vs ( P <0.01), increased PEP ( P <0.05), significantly increased PEP/ET ( P <0.01). After revascularization, patients with CAD had significantly increased Vs ( P <0.01), decreased PEP ( P <0.05), significantly decreased PEP/ET ( P <0.01), significantly increased Vmva ( P <0.01). EF had a good linear relation to Vmva ( r =0.81, P <0.01)after revascularization. Conclusion PWDTI can real time detect changes of myocardiac motion and quantify regional and global left ventricular systolic function before and after revascularization.