活血化瘀法为主治疗白细胞减少症23例近期疗效观察

本文用活血化瘀中药当归、川芎、红花、鸡血藤、赤芍为主治疗白细胞减少症23例,有效率为91.30%。疗效机理可能是此类中药促进 DNA 合成,促进了造血细胞的增殖、分化,成熟和释放;或此类中药的缩脾作用减轻了脾脏因素对白细胞的影响;是否还通过其免疫调节作用而发挥疗效,有待研究。

Observation on Short-Term Effect of 23 Cases of Leukopenia Treated Mainly with Chinese Huo Xue Hua Yu Drugs

Twenty-three cases with leukopenia were treated with Chinese Hue Xue Hua Yu drugs,i.e.,drugs with the action of activating blood flow and eliminating blood stasis:Radix Angelicae sinensis,Rhizoma Ligustici Chuanxiong,Flos Carthami,Caulis spatholobi and Radix paeoniae Rubra. Twenty-one of the patients were hospitalized,the others were out-patients,age ranging from 21 to 55 years. Seven of them were male.All of them had diagnosis established by means of clinical and laboratory examination. Their white-cell count had been as high as 1,800 to 3,800 before the treatment with an average value of 3,228.26 ±542.47(M±SD).The course of treatment was 6 days to 14 months.Improvement was observed from 2 to 48 days, 12 days on the average.The result was excellent in 8 cases,good in 13 cases,and poor in 2 cases.The total effective rate was 21/23(91.30%).White-cell count ofaU patients increased to 4,473±1,299.11(M±SD)after treatment.The therapeutic mechanism was supposed to be promotion of synthesis of DNA brought about by action of Chinese drugs which improved the reproduction,differentiation,maturity and release of the stem cells,stimulated the contraction of spleen and reduced the influence of splenic factor on white-cell.There was also probability that immunity-regulating effect of the Chinese drugs eliminated or reduced immunopathologic injury of white-cells.