个性特征与功能性消化不良的关系

背景:焦虑、抑郁与神经质个性有着密切的联系,并与功能性胃肠病的发病密切相关。目的:调查功能性消化不良(FD)患者与健康人在个性和焦虑、抑郁状态方面的差异,探讨个性特征与FD发病的关系。方法:采用龚耀先修订的艾森克人格问卷(EPQ成人版)和Zung焦虑自评量表(SAS)、抑郁自评量表(SDS)对130例FD患者和110名健康人进行评分,比较两组受试者在精神质、神经质、内外向和掩饰质四个特质个性,以及焦虑、抑郁情绪方面的差异。结果:FD患者的神经质和SAS、SDS分值显著高于健康对照组(P<0.001),内外向分值显著低于健康对照组(P<0.05),两组间精神质和掩饰质分值则无显著差异(P>0.05)。FD患者个性异常的发生率显著高于健康对照组,其神经质评分与SAS、SDS评分呈正相关(P<0.001和P<0.05)。结论:神经质和内向个性与FD密切相关,可能是FD的病理心理学特征和病因之一。

Relationship between Personality Characteristics and Functional Dyspepsia

Background: Anxiety and depression are closely associated with neurotic personality, and are involved in the pathogenesis of functional gastrointestinal diseases. Aims: To investigate the differences of personality trait, anxiety and depression between functional dyspepsia (FD) patients and the healthy subjects, so as to study the relationship between personality characteristics and the pathogenesis of FD. Methods: One hundred and thirty FD patients and 110 healthy subjects were enrolled in this study. The personalities (psychoticism, neuroticism, extro-introversion and lie) of all subjects were assessed by revised Eysenck Personality Questionnaire (EPQ, adult edition), and the anxiety and depression were evaluated by Zung self-rating anxiety scale (SAS) and self-rating depressive scale (SDS), respectively. Results: The scores of neuro-ticism, SAS and SDS were significantly higher in FD patients than those in healthy controls (P<0.001); the score of extro-introversion was markedly lowered in FD patients than that in healthy controls (P<0.05). No significant difference was found in the scores of psychoticism and lie between the two groups (P>0.05). The incidence of abnormal personalities in FD patients was obviously higher than that in healthy controls, the score of neuroticism in FD patients was positively correlated with the SAS and SDS scores (P<0.001 and P<0.05). Conclusions: Neurotic and introversive personality trait are closely correlated with FD, and may be one of the psychopathological features and the causes of FD.