间充质-上皮转化在女性生殖系统中的研究进展

间充质-上皮转化(mesenchymal-epithelial transition,MET)是间充质细胞、上皮细胞相互转化的一种生物学特性,是人体多种生物学过程的基础,在女性生殖系统形成和发育过程中扮演了关键角色.间充质细胞向上皮细胞的转化在胚胎发育早期阶段就已开始,并且参与了多个器官和组织的形成.此外,MET不仅帮...

Research Progress of Mesenchymal-Epithelial Transition in Female Reproductive System

Mesenchymal epithelial transition(MET)is a biological characteristic of the transformation between mesenchymal cells and epithelial cells.It is the basis of many biological processes in the human body.It also plays a key role in the formation and development of the female reproductive system.MET begins at the early stage of embryo development,which is involved in the formation of multiple organs and tissues.In addition,MET not only helps the physiological regeneration of endometrial epithelial cells and the decidualization to regulate the adhesion and implantation of embryos,but also plays an important role in the pathological process of reproductive diseases such as endometriosis and tumors.This article reviews the research progress related to MET in order to provide ideas and directions for the research on the structure and function of female reproductive system and the prevention and treatment of reproduction-related diseases.