Antibody-dependent cellular cytotoxicity in chronic human Chagas disease |
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| Authors: | J.C. VOLTARELLI,R.P. FALCÅ O,J. SANTANA DA SILVA |
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| Affiliation: | Departments of Clinical Medicine and of Microbiology, Immunology and Parasitology, School of Medicine, Ribeirao Preto, University of Såo Paulo, Brazil |
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| Abstract: | Antibody-dependent cellular cytotoxicity mediated by granulocytes (ADGC) or lymphocytes (ADLC) was assessed in 23 patients with chronic Chagas disease. The results of ADGC against T. cruzi were normal. ADLC against chicken erythrocytes was significantly reduced in patients as compared with normal controls. Possible causes of this abnormality were investigated. |
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| Keywords: | antibody-dependent cell cytotoxicity killer cells antilymphocyte antibodies Chagas disease |
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