| 染色体检查在恶性胸腔积液诊断中的价值 |
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| 引用本文： | 吕喜英,张秀琴,刘兰芳. 染色体检查在恶性胸腔积液诊断中的价值[J]. 临床荟萃, 2004, 19(18): 1029-1031 |
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| 作者姓名： | 吕喜英 张秀琴 刘兰芳 |
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| 作者单位： | 承德医学院附属医院,肿瘤内科,河北,承德,067000;承德医学院附属医院,肿瘤内科,河北,承德,067000;承德医学院附属医院,肿瘤内科,河北,承德,067000 |
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| 摘 要： | 目的探讨染色体检查在胸腔积液鉴别诊断中的价值。方法采用常规染色体定性检查和流式细胞术(FCM)DNA定量分析两种方法检查胸腔积液中的染色体，并进行比较。结果常规染色体检查对恶性胸腔积液诊断的特异性为98．2％，敏感性为88．9％；FCM法特异性为100％，敏感性为93．8％；二者联合的特异性为100％，敏感性为86．4％。结论常规染色体检查和FCM DNA定量分析两种方法联合检查对胸腔积液的鉴别诊断提供了可靠的诊断依据。
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| 关 键 词： | 胸腔积液 恶性 染色体 染剂和染色法 流式细胞术 |
| 文章编号： | 1004-583X(2004)18-1029-03 |
Diagnostic value of chromosome detection in malignant pleural effusions |
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| LU Xi-ying,ZHANG Xiu-qin,LIU Lan-fang. Diagnostic value of chromosome detection in malignant pleural effusions[J]. Clinical Focus, 2004, 19(18): 1029-1031 |
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| Authors: | LU Xi-ying ZHANG Xiu-qin LIU Lan-fang |
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| Affiliation: | LU Xi-ying,ZHANG Xiu-qin,LIU Lan-fang Department of Tumor,the Affiliated Hospital of Chengde Medical College,Chengde 067000,China |
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| Abstract: | Objective To evaluate the diagnostic value of chromosome in pleural effusions. Methods The chromosome was measured by routine staining-location method and flow cytometry(FCM) DNA qualification in pleural effusions. Results The chromosome specificity and sensitivity were 90.9% and 88.9% by routine method, and by FCM they were 100% and 93.9%;they were 100% and 86.4% by joining the two methods. Conclusion The joining detection to the chromosome with routine and FCM provides a dependable method for diagnosis of pleural effusions. |
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| Keywords: | pleural effusion malignant chromosomes stains and staining flow cytometry |
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