TACE联合RFA治疗中晚期原发性肝癌的疗效观察

目的：探讨肝动脉栓塞化疗（TACE）联合多电极射频治疗（RFA）中晚期原发性肝癌的临床疗效。方法：237例单发肿瘤直径5～8cm的中晚期原发性肝癌患者分为单纯RFA组69例和TACE联合RFA组168例，RFA治疗后2周通过超声造影对两组治疗效果进行评估。结果：TACE联合RFA治疗的168例患者中超声造影显示91例（53％）始终无增强，呈边界清楚的低回声，诊断肿瘤完全灭活；77例表现为边缘部分区域的结节状、月牙状或不规则形增强区。而单纯RFA治疗的69例患者中超声造影显示23例（33％）肿瘤完全灭活。结论：TACE联合RFA治疗中晚期原发性肝癌比单纯RFA治疗的疗效更好。

Clinical observation of the efficacy of transcatheter arterial chemoembolazition combined radio-frequency ablation in primary liver cancer

Objective:To evaluate clinical efficacy of transcatheter arterial chemoembolazition sequentially combined radiofrequency ablation in the treatment of advanced primary lier cancer.Methods:Two hundred and thirty-seven cases with single advanced primary liver cancer(5-8cm)were divided into RFA group(n=69)and RFA combined with TACE group(n=168).The efficacy of the two groups through contrast-enhanced ultrasound were evaluated two weeks later.Results:According the imagement of contrast-enhanced ultrasound,the complete necrosis rate of tumor was 33%(23/69)in RFA,but it was 53%(91/169)in RFA combined with TACE group.Conclusion:Better therapeutic efficacy is expected by RFA combined with TACE in advanced primary liver cancer.