沈阳市高危人群艾滋病、梅毒、肝炎的调查分析

目的 了解辽宁省高危人群艾滋病、梅毒和肝炎的感染现状。方法 应用固相酶免疫测定（ELISA）法或间接血凝法分别检测了488名吸毒者、暗娼和 STD门诊患者及2 000例普通患者血清中 HIV抗体、HBsAg、抗-HBs、抗-HCV、抗梅毒抗体。结果 吸毒者丙型肝炎感染率为47.5％,显著高于暗娼（6.8％）和 STD门诊患者（1.4％）（P<0.01）;吸毒者、暗娼、STD门诊患者梅毒感染率均高于普通患者,且STD门诊梅毒感染率显著高于吸毒者（P<0.01）;吸毒者、暗娼、STD人群和普通患者各组间抗-HBs阳性率无显著差异（P>0.05）;本次调查未发现AIDS患者/HIV感染者。结论 辽宁省高危人群梅毒、丙型肝炎感染率较高,应加强高危人群管理,防止艾滋病在辽宁省的流行。

Survey of HIV, HBV, HCV and syphilis infection among risk groups in Shenyang

Objective To understand the prevalence of HIV infection, syphilis and hepatitis among high risk poputation in Liaoning Province. Methods Serum samples of 2000 general patients and 488 drug users, prostitutes and STD clinic outpatients were detected with ELISA method for HBsAg, HBsAb, anti - HCV antibody and syphilis antibody. Results The hepatitis C prevalence rate among drug users is 47.5% ,significantly higher in prostitutes(6.8% )and STD clinic out-pationts (1.4 % ) ( P <0.01); the syphilis prevalence rates among drug users, prostitutes or STD clinic out-patients were higher than that in general patients ,and the syphilis prevalence rate in STD clinic out - patients is much higher than that in drug users ( P <0.01);there is no significant difference in the HBsAb positive rates among the drug users, the prostitutevs, the STD patients and the general patients ( P >0.05) ;no HIV positive was found in this survey. Conclusion The prevalence rate of syphilis and hepatitis C among high risk groups in Liaoning province is very high,so the efficient interventions must be taken to prevent the transmission of HIV in our province.