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氨酚羟考酮片用于疼痛治疗的回顾性分析
引用本文:高钧,赵国伟,周宁.氨酚羟考酮片用于疼痛治疗的回顾性分析[J].中国新药杂志,2007,16(16):1308-1310.
作者姓名:高钧  赵国伟  周宁
作者单位:中国康复研究中心药剂科,北京,100068
摘    要:目的:探讨氨酚羟考酮片(泰勒宁片)用于疼痛镇痛效果及其安全性。方法:选取口服泰勒宁片的患者100例,观察疼痛缓解程度及其不良反应。结果:泰勒宁片用于疼痛患者中度疼痛缓解显效率为81.0%,有效率为19.0%;重度疼痛患者显效率为65.5%,有效率为24.1%;总有效率为94.0%。有头晕、嗜睡、恶心、呕吐、便秘、皮肤瘙痒、皮疹、呼吸抑制等不良反应。结论:泰勒宁片用于治疗疼痛疗效确切,不良反应小。

关 键 词:氨酚羟考酮片  疼痛  疗效  药物不良反应
文章编号:1003-3734(2007)16-1308-03
收稿时间:2007-06-26
修稿时间:2007年6月26日

Retrospective analysis of oxycodone and acetaminophen tablets for the treatment of pain
GAO Jun,ZHAO Guo-wei,ZHOU Ning.Retrospective analysis of oxycodone and acetaminophen tablets for the treatment of pain[J].Chinese Journal of New Drugs,2007,16(16):1308-1310.
Authors:GAO Jun  ZHAO Guo-wei  ZHOU Ning
Institution:Department of Pharmacy, China Rehabilitation Research Center, Beijing 100065, China
Abstract:Objective:To assess the efficacy and safety of oxycodone and acetaminophen tablets(Tylox) for the treatment of pain.Methods:100 patients with different pain were given Tylox.Improvements in pain and adverse effects were observed.Results:Tylox in pain treatment was good.Moderate pain relief and complete relief rate were 81.0% and 19.0% respectively.Serious pain relief rate were 65.5% and 24.1% respectively.Total relief rate was 94.0%.Only a few patients had adverse reaction,including dizziness,lethargy,nausea,vomiting,constipation,pruritus,skin eruption and respiratory depression.Conclusion:Tylox has definite effect and slight adverse reaction in pain treatment.
Keywords:oxycodone and acetaminophen tablets  pain  therapeutic effect  adverse reaction
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