| 正交试验优选无糖银菊颗粒剂工艺 |
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| 引用本文： | 苏维辉,陈木水,任结梅.正交试验优选无糖银菊颗粒剂工艺[J].中药材,2004,27(10):770-772. |
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| 作者姓名： | 苏维辉 陈木水 任结梅 |
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| 作者单位： | 1. 广州市第一人民医院,广州,510180
2. 广州中医药大学第一附属医院,广州,510405 |
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| 摘 要： | 目的:优选无糖银菊颗粒剂中氯原酸提取工艺.方法:用正交试验方法设计水提取工艺,以提取物中氯原酸含量为测定指标,考察提取次数,加水量和醇沉时乙醇浓度三个因素对有效成分氯原酸提取的影响.结果:最佳工艺为10倍量水提3次,以70%乙醇沉淀杂质,使制剂的质量得以控制.
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| 关 键 词： | 正交设计 颗粒剂 氯原酸 |
| 修稿时间： | 2004年2月26日 |
Study on Optimal Extraction Process of Yinju Sugarless Granules with Orthogonal Design |
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| Su Weihui,Chen Mushui,Ren Jiemei.Study on Optimal Extraction Process of Yinju Sugarless Granules with Orthogonal Design[J].Jorunal of Chinese Medicinal Materials,2004,27(10):770-772. |
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| Authors: | Su Weihui Chen Mushui Ren Jiemei |
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| Institution: | The First People' s Hosptil of Guangzhou, Guangzhou 510180. |
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| Abstract: | Objective:To study the extxtraction process of chlorogenic acid from Yinju sugarless granules.Methods:The optimal extraction process was selected with orthogonal design.The content of chlorogenic acid in the extract was detremined.Results:The content of chlorogenic acid was influenced by frequency of extraction,the quantity of water and the concentration of ethanol.Conclusions:The optimal extraction process is extraction 3 times with 10 times water and with 70% ethanol. |
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| Keywords: | Orthogonal design Granules Chlorogenic acid |
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