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Delayed and Synchronous Recurrence of Breast Cancer Metastases in Multiple Organs
Authors:Takashi Owaki  Satoru Hashimoto  Hajime Umezu  Shuji Terai
Affiliation:1.Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan; 2.Division of Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Japan
Abstract:The most common sites of breast cancer metastasis include the lymph nodes, bones, lungs, liver, and brain. Gastrointestinal tract metastasis is rarely seen, and hypopharyngeal metastasis is extremely rare. We herein report a case of late distant recurrence of breast cancer and synchronous metastasis to the hypopharynx, stomach, ileum, bones, and lymph nodes almost 24 years after surgery. To our knowledge, this is the first case of synchronous metastasis to the hypopharynx, gastrointestinal tract, and other organs, especially after a long interval following primary mastectomy.
Keywords:breast cancer   gastrointestinal tract   hypopharynx   immunohistochemistry   metastasis   late recurrence
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