中国部分地区人类免疫缺陷病毒感染者/艾滋病患者合并感染HBV或/和HCV的研究进展

分析德宏傣族景颇族自治州（简称“德宏州”）人类免疫缺陷病毒（HIV）双阳性夫妻合并丙型肝炎病毒（HCV）感染特征和影响因素。

利用2016—2019年德宏州新报告的HIV双阳性夫妻病例疫情卡片，收集不同性别配偶的一般人口学信息、接触史、HCV感染情况等资料，探究HIV双阳性夫妻特征和合并HCV感染的情况。

纳入的160对HIV双阳性夫妻中，有46例（28.8%）男性、14例（8.8%）女性HIV感染者合并感染HCV。单因素分析显示，HIV确诊年龄<40岁、景颇族、缅甸籍、未接受系统教育、农民和有注射毒品史的男性配偶合并HCV感染率更高；HIV确诊年龄<40岁、景颇族和缅甸籍的女性配偶合并HCV感染率更高。男性配偶的多因素logistic回归分析显示，景颇族（OR=3.76，95%CI：1.14~12.39）和注射毒品史（OR=29.46，95%CI：2.42~358.42）会增加HCV合并感染率。

德宏州HIV双阳性夫妻HCV合并感染率较高，应针对民族特异性因素和HIV双阳性夫妻不同性别配偶的暴露特点，制定有效的干预策略以减少疾病负担。

Research progress of HIV infection/AIDS patients co-infected with HBV and/or HCV

To determine the characteristics and influencing factors of hepatitis C virus （HCV） co-infection among HIV concordant couples in Dehong Prefecture.Using the data of newly reported HIV concordant couples in Dehong Prefecture from 2016 to 2019， we collected the demographic characteristics， exposure history， and HCV infection to determine the characteristics of HCV co-infection among HIV concordant couples.Among the 160 HIV concordant couples included in the study， 46 （28.8%） males and 14 （8.8%） females were co-infected with HCV. The prevalence of HIV-HCV co-infection was higher among the male spouses who were diagnosed less than 40， Jingpo ethnic， Burmese， illiteracy， farmers， and intravenous drug users. In contrast， the prevalence of HIV-HCV co-infection was higher among the female spouses who were diagnosed less than 40， Jingpo ethnic， and Burmese. Logistic regression analysis among male spouses showed that the Jingpo ethnic and intravenous drug users had higher risk of HCV co-infection.HIV concordant couples in Dehong Prefecture have high prevalence of HIV-HCV co-infection. Effective intervention strategies should be developed based on ethnic-specific factors and exposure characteristics among male and female spouses of HIV concordant couples.