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| 人参皂苷Rb1的药理活性研究进展 | |
| 引用本文： | 贾继明,王宗权,吴立军,吴以岭. 人参皂苷Rb1的药理活性研究进展[J]. 中国中药杂志, 2008, 33(12): 1371-1377 |
| 作者姓名： | 贾继明 王宗权 吴立军 吴以岭 |
| 作者单位： | 1. 沈阳药科大学,中药学院,辽宁,沈阳,110016;河北省中西医结合医药研究院,河北,石家庄,050035 2. 河北省中西医结合医药研究院,河北,石家庄,050035 3. 沈阳药科大学,中药学院,辽宁,沈阳,110016 |
| 基金项目： | 国家重点基础研究发展计划项目 |
| 摘 要： | 人参皂苷Rb1是人参二醇系皂苷的代表成分之一，属于达玛烷型三萜皂苷类化合物, 主要分布于五加科植物中，具有多种生物活性。作者从心血管系统、抗衰老、逆转肿瘤细胞耐药、肿瘤化疗的辅助用药、促进周围神经再生等几个方面，对人参皂苷Rb1近10年来的研究进展进行了综述。 |
| 关 键 词： | 人参皂苷Rb 药理活性 心血管系统 抗衰老 |
| 收稿时间： | 2007-09-03 |
Advance of pharmacological study on ginsenoside Rb1 |
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| JIA Ji-ming; WANG Zong-quan; WU Li-jun; WU Yi-ling. Advance of pharmacological study on ginsenoside Rb1[J]. China Journal of Chinese Materia Medica, 2008, 33(12): 1371-1377 | |
| Authors: | JIA Ji-ming WANG Zong-quan WU Li-jun WU Yi-ling |
| Affiliation: | School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang 110016, China. |
| Abstract: | Ginsenoside Rb1 is a representative component of panaxadiol saponins, which belongs to dammarane-type tritepenoid saponins and mainly exists in family araliaceae. It has been reported that ginsenoside Rb1 has diverse biological activities. In this paper, the research development in recent decade on its pharmacological effects of cardiovascular system, anti-senility, reversing multi-drug resistance of tumor cells, adjuvant anti-cancer chemotherapy, promoting peripheral nerve regeneration, et al, are reviewed. |
| Keywords: | ginsenoside Rb pharmacological study cardiovascular system anti-senility |
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